CWRU School of MedicineVisit Li Lab
Jin LabFulai Jin, Principal Investigator
Jin LabFulai Jin, Principal Investigator

Jin Lab

We study gene regulation, chromatin organization, and single-cell genomics to understand how regulatory programs shape cellular function and disease.

Research

Transcriptional Regulation

Enhancer, promoter, and transcription-factor programs that establish cell identity and response.

Epigenetics and Epigenomics

Chromatin states, histone marks, and regulatory annotations across development and disease contexts.

3D Genome Architecture

Genome folding, long-range contacts, and spatial regulatory mechanisms measured with chromosome conformation assays.

Single-Cell Genomics

Cell-state heterogeneity and lineage dynamics resolved with single-cell and multi-omic measurements.

Computational and Systems Biology

Algorithms, benchmarking, and reproducible resources for interpreting high-dimensional genomic data.

Publications

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Resources

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HiCorr

A Hi-C data bias-correction pipeline

DeepLoop

A deep-learning-based signal enhance method for robust chromatin interaction mapping

SCORE

Single-cell Chromatin Organization Representation and Embedding

Va3DE

Variational 3D Embedding for Single-Cell Hi-C Clustering