Transcriptional Regulation
Enhancer, promoter, and transcription-factor programs that establish cell identity and response.
Jin Lab
We study gene regulation, chromatin organization, and single-cell genomics to understand how regulatory programs shape cellular function and disease.
Research
Epigenetics and Epigenomics
Chromatin states, histone marks, and regulatory annotations across development and disease contexts.
3D Genome Architecture
Genome folding, long-range contacts, and spatial regulatory mechanisms measured with chromosome conformation assays.
Single-Cell Genomics
Cell-state heterogeneity and lineage dynamics resolved with single-cell and multi-omic measurements.
Computational and Systems Biology
Algorithms, benchmarking, and reproducible resources for interpreting high-dimensional genomic data.
Publications
All publications2026
Cross-platform Hi-C meta-analysis identifies functional insulators that actively block enhancer-promoter interactions
Apr 2026
Proinsulin regulators identified with CRISPR screen and in vivo mouse QTL mapping
Oct 2025
STAG2 regulates polycomb and differentiation in urothelial precursors and bladder cancer
Resources
All resourcesHiCorr
A Hi-C Data Bias-Correction Pipeline
Open resourceDeepLoop
A deep-learning-based signal enhance method for robust chromatin interaction mapping
Open resourceSCORE
Single-cell Chromatin Organization Representation and Embedding
Open resourceContact
Jin Lab is actively seeking motivated students and postdocs with experimental and/or computational experience.